糖尿病患者心率变异性分析的临床研究

目的探讨糖尿病(DM)合并自主神经病变的患者心率变异性(HRV)变化的临床意义。方法回顾性筛选出各30例有自主神经病变症状和无自主神经病变症状的DM患者分为有症状(DMⅠ)组和无症状(DMⅡ)组,30例正常对照组进行HRV变化研究及回顾性分析。结果DM自主神经病变(DAN)患者各时域及频域分析指标均较正常对照组降低(P<0.05或P<0.01)。结论DAN患者在尚未出现自主神经临床症状时HRV频域指标就已有了明显的降低,合并有自主神经症状患者下降更为显著,HRV分析是衡量DM患者合并自主神经病变有效的客观指标,是提高DAN早期诊断率的有效途径。

Clinical Analysis of Heart Rate Variability in Patients with Diabetes Mellitus

Objective To explore the Clinical significance of heart rate variability (HRV) in patients with diabetic autonomic neuropathy (DAN). Methods Clinical data and HRV were reviewed in 30 cases with DAN (group I) and 30 diabetic cases without DAN (group Ⅱ), and 30 normal cases were in control group. Results The parameters various time and territory of patients with DAN decreased compared with control group (P<0.05 or P<0.01). Conclusion HRV in patients with DAN but without clinical symptoms decreased significantly, in patients with DAN and clinical symptoms decreased more significantly. HRV analysis is an effective objective parameter to measure DAN lesions in patients with DM, may be used to efficiently detect DAN in early stage.