Whole-Genome Sequencing of Shiga Toxin–Producing Escherichia coli OX18 from a Fatal Hemolytic Uremic Syndrome Case |
| |
| Authors: | Kenichi Lee Atsushi Iguchi Kazuhiro Uda Sohshi Matsumura Isao Miyairi Kenji Ishikura Makoto Ohnishi Junji Seto Kanako Ishikawa Noriko Konishi Hiromi Obata Ichiro Furukawa Hiromi Nagaoka Hirotaka Morinushi Natsuki Hama Ryohei Nomoto Hiroshi Nakajima Hideaki Kariya Mitsuhiro Hamasaki Sunao Iyoda |
| |
| Abstract: | We report a fatal case of hemolytic uremic syndrome with urinary tract infection in Japan caused by Shiga toxin–producing Escherichia coli. We genotypically identified the isolate as OX18:H2. Whole-genome sequencing revealed 3 potentially pathogenic lineages (OX18:H2, H19, and H34) that have been continuously isolated in Japan. |
| |
| Keywords: | Bacteria, E. coli, Og-typing, OX18, Shiga toxin– producing Escherichia coli, foodborne pathogens, STEC, whole-genome sequencing, Japan, food safety, enteric infections |
|
|
