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Longevity of Middle East Respiratory Syndrome Coronavirus Antibody Responses in Humans,Saudi Arabia |
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| Authors: | Abeer N. Alshukairi Jincun Zhao Maha A. Al-Mozaini Yanqun Wang Ashraf Dada Salim A. Baharoon Sara Alfaraj Waleed A. Ahmed Mushira A. Enani Fatehi E. Elzein Nazik Eltayeb Laila Layqah Aiman El-Saed Husam A. Bahaudden Abdul Haseeb Sherif A. El-Kafrawy Ahmed M. Hassan Najlaa A. Siddiq Ibtihaj Alsharif Isamel Qushmaq Esam I. Azhar Stanley Perlman Ziad A. Memish |
| Abstract: | Understanding the immune response to Middle East respiratory syndrome coronavirus (MERS-CoV) is crucial for disease prevention and vaccine development. We studied the antibody responses in 48 human MERS-CoV infection survivors who had variable disease severity in Saudi Arabia. MERS-CoV–specific neutralizing antibodies were detected for 6 years postinfection. |
| Keywords: | Middle East respiratory syndrome coronavirus MERS-CoV coronaviruses viruses Middle East respiratory syndrome MERS antibody responses longevity humans patients disease severity zoonoses Saudi Arabia |