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蛞蝓提取物对人肺癌细胞A549的抑制作用
引用本文:曾振东,韦金育,曾翠琼,俸曙光,杨增艳. 蛞蝓提取物对人肺癌细胞A549的抑制作用[J]. 辽宁中医杂志, 2012, 0(7): 1335-1336
作者姓名:曾振东  韦金育  曾翠琼  俸曙光  杨增艳
作者单位:广西民族医药研究院
基金项目:国家自然科学基金资助项目(30960508)
摘    要:目的:了解蛞蝓提取物对人肺癌细胞A549的抑制作用及对细胞形态学的影响。方法:用MTT法测定蛞蝓提取物对A54 9细胞的增殖抑制率,并观察其形态学变化。结果:蛞蝓提取物能抑制A549细胞的增殖,抑制率为11.1%~66.51%;镜下可见肺癌细胞呈变小、变少、破碎裂解等变化。结论:蛞蝓提取物对人肺癌A549细胞有显著的抑制作用。

关 键 词:蛞蝓提取物  肺癌细胞A549  抑制作用

The Inhibitory Effects of Land Slug Extractive on A549 Cell
ZENG Zhen-dong,WEI Jin-yu,ZENG Cui-qiong,FENG Shu-guang,YANG Zeng-yan. The Inhibitory Effects of Land Slug Extractive on A549 Cell[J]. Liaoning Journal of Traditional Chinese Medicine, 2012, 0(7): 1335-1336
Authors:ZENG Zhen-dong  WEI Jin-yu  ZENG Cui-qiong  FENG Shu-guang  YANG Zeng-yan
Affiliation:(Guangxi Institute of Folk Medicine,Nanning 530001,Guangxi,China)
Abstract:Objective:To find out the inhibitory effects of land slug extractive on A549 cell and the effect on cell morphology.Methods:MTT method was used to detect inhibition ratio to A549 cell and the morphological changes were observed by electron microscopy.Results:Land slug extractive could inhibit the proliferation of A549 cell,the suppression ratio was 11.1%~66.51%.It showed lung cancer cell diminishing,tailing off and schizolysis.Conclusion:Land slug extractive possesses the obvious effects on A549 cell.
Keywords:land slug extractive  a549 cell  inhibitory effects
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