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八桂民族药防治肝纤维化研究的进展
引用本文:张园,王玖恒,李景强,彭岳,赵铁建.八桂民族药防治肝纤维化研究的进展[J].辽宁中医杂志,2012(9):1881-1883.
作者姓名:张园  王玖恒  李景强  彭岳  赵铁建
作者单位:广西中医药大学研究生学院;广西中医药大学基础医学院
基金项目:国家自然科学基金课题(30760321,81160553);广西科学研究与技术开发计划课题(桂科计字[2009]92-3-1)
摘    要:文章列举当前研究和有代表性的八桂民族药白花丹、排钱草、半枝莲、桂莪术和桂郁金在抗肝纤维化的进展,侧重反映广西地方学者在研究上述八桂民族药方面的最新成果。详述了白花丹在防治肝纤维化等方面的研究近况,并阐述了排钱草提取物抗肝纤维化作用;半枝莲提取物对肝损伤的保护功能;桂莪术对肝组织病变的减轻作用;桂郁金提取物具有抑制HSC-LX2细胞增殖、诱导细胞发生凋亡的能力。通过对上述八桂民族药的综述拟说明其抗肝纤维化的研究价值及意义。

关 键 词:八桂民族药  传统中药  肝纤维化

Study Progress on Bagui National Drug Prevention and Treatment of Liver Fibrosis
ZHANG Yuan,WANG Jiu-heng,LI Jing-qiang,PENG Yue,ZHAO Tie-jian.Study Progress on Bagui National Drug Prevention and Treatment of Liver Fibrosis[J].Liaoning Journal of Traditional Chinese Medicine,2012(9):1881-1883.
Authors:ZHANG Yuan  WANG Jiu-heng  LI Jing-qiang  PENG Yue  ZHAO Tie-jian
Institution:1.Graduate School,Guangxi University of Chinese Medicine,Nanning 530001,Nanning,China; 2.School of Basic Medicine,Guangxi University of Chinese Medicine,Nanning 530001,Nanning,China)
Abstract:This article lists the current research progress of liver fibrosis of the representative Bagui national drugs including plumbago zeylanica,beautiful phyllodium branchlet and leaf,Herba Scutellariae Barbatae,rhizoma curcumae kwangsiensis,radices curcumae,focusing on academics latest results in the study on Guangxi Bagui national drugs.Details of plumbago zeylanica against liver fibrosis and other aspects were made,and it described the anti liver fibrosis function of beautiful phyllodium branchlet and leaf extract;liver injury protection of Herba Scutellariae Barbatae extract;reducation effect on liver lesions of radices curcumae;inhibiting HSC-LX2 cells and the ability to induce apoptosisof rhizoma curcumae kwangsiensis extract.Based on the above overview of the proposed Bagui national drugs,its anti-hepatic fibrosis research value and significance were explained.
Keywords:Bagui national drugs  traditional Chinese medicine  liver fibrosis
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