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大鼠液压冲击脑外伤模型的病理学分级研究
引用本文:陈风华,万新.大鼠液压冲击脑外伤模型的病理学分级研究[J].湖南医科大学学报,2000,25(2):194-196.
作者姓名:陈风华  万新
摘    要:目的:研究大鼠液压冲击脑外伤模型的病理改变,并对其进行分级,旨在阐明液脑外伤模型的病理学特点。方法:采用自行改进的液压冲击模型装置产生大鼠液压冲击脑外伤模型,对大鼠脑组织进行肉我镜观察。结果:肉眼、光镜下出现可分级的病理学改变。结论:本模型的病理学分级适用于实验和临床上损伤程度的评估。

关 键 词:颅脑损伤  病理学  疾病模型  分级  液压冲击伤

Study of the fluid-percussion graded model of experimental brain injury in rats]
F H Chen,X Wan,J S Fang.Study of the fluid-percussion graded model of experimental brain injury in rats][J].Bulletin of Hunan Medical University,2000,25(2):194-196.
Authors:F H Chen  X Wan  J S Fang
Institution:Department of Neurosurgery, Xiangya Hospital, Hunan Medical University, Changsha 410008.
Abstract:OBJECTIVE: To study the histopathological aspects of the fluid-percussion graded model of experimental brain injury in rats and the relationship between the fluid-percussion graded model and the clinical grades of brain injury. METHODS: The graded model of rats was set up by using the device of the improved fluid-percussion model, then we observed the changes of brain tissue of rats. RESULTS: The fluid-percussion graded model of experimental brain injury could be pathologically graded. CONCLUSION: The pathological grade of the fluid-percussion graded model can be used to evaluate the degree of brain injury in clinic and in experiments.
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