2002～2011年揭阳地区结直肠癌流行病学研究

目的收集主要医院收治的结直肠癌病例,分析了解近10年(2002～2011年)揭阳地区结直肠癌流行病学特征的变化规律和趋势。方法总结分析揭阳地区主要医院即业务量最大的三家医院普宁市人民医院、普宁市华侨医院、揭阳市人民医院2002～2011年经病理确诊的结直肠癌3,015例,通过收集病历资料,计算每年发病率及不同年龄组别和不同肿瘤部位发病例数及所占比例。结果男、女性结肠癌标化发病率从2002年的3.58/10万及3.31/10万上升到2011年的9.55/10万和9.03/10万,10年平均上升11.52%和11.79%;总标化发病率10年平均上升11.63%。男、女性直肠癌标化发病率从2002年的2.46/10万及3.70/10万上升到2011年的16.73/10万及10.15/0万,10年平均上升23.75%及11.86%;直肠癌总标化发病10年平均上升17.93%。男、女性结直肠癌发病率呈随年龄增加而上升的趋势,高发年龄在50岁以上年龄组。在发病部位方面,直肠癌的比例从2002年的46.79%上升至2011年的59.03%,右半结肠癌的比例也从18.3%上升至23.35%。结论进10年来,揭阳地区结直肠癌的发病率不断上升;结肠癌男女性别比呈下降趋势,而直肠癌则呈上升趋势;直肠癌和升结肠癌比例不断上升。

An epidemiological study on colorectal cancer from 2002 to 2011 in Jieyang Area

Objective To collect colorectal cases confirmed by pathology from 2002 to 2011 in the main hospitals in Jieyang area , and investigate the epidemiological characteristics of colorectal cancer in such area. Methods Clinical data of colorectal cancer cases confirmed pathologically from 2002 to 2011 in the main hospitals in Jieyang area were collected. The epidemiological characteristics including rude incidence, standardized incidence , male to female ratio , tumor location specific rate were analyzed. Results A total of 3,015 colorectal cases were registered. The standardized incidence of colon cancer in males and females increased from 3.58 / 100 ,000 and 3.31 / 100,000 in 2002 to 9.55 / l00,000 and 9.03 / 100,000 in 2011, with an average incidence increase of 11.52% and 11.79% respectively. The average increase of standardized incidence of colon cancer was 11.63% .The standardized incidence of rectal cancer in males and females increased from 2.46 / 100 ,000 and 3.70 / 100,000 in 2002 to 16.73 / 100,000 and 10.15 / 100,000 in 2011 with an average incidence increase of 23.75% and 11.86% respectively. The average increase of standardized incidence of rectal cancer was 17.93%. The incidences of colon and rectal cancer in both males and females increased with age , and age-specific incidence was highest in the age group more than 50 years. The proportion of rectal cancer increased from 46.79% in 2002 to 59.03% in 2011, while the proportion of ascending colon cancer from 18.3% in 2002 to 23.35% in 2011. Conclusions In the past 10 years, the incidence of colorectal cancer increased in Jieyang area. The male to female ratio decreased in colon cancer while increased in rectal cancer. The proportions of ascending colon cancer and rectal cancer increased.