中医辨证结合西医分期治疗急性脑梗死临床研究

目的观察中西医结合治疗急性脑梗死的临床疗效。方法279例急性脑梗死患者随机分为两组,对照组140例采用西医分期治疗,治疗组139例在此基础上结合中医辨证治疗。采用神经功能缺损评分量表（CSS）、NIHSS评分、Rankin残障评级和Barthel指数进行疗效评价。结果90天试验终点时间治疗组总有效率73.38%（102/139例）,优于对照组的61.43%（86/140例）（P〈0.05）。NIHSS评分改善≥40%者对照组66例（47.14%）,治疗组80例（57.55%）;Rankin评级0-2级者对照组65例（46.43%）,治疗组78例（56.12%）;Barthel指数评分≥85分者对照组60例（42.86%）,治疗组71例（51.08%）;CSS改善≥46%者对照组为61例（43.57%）,治疗组为72例（51.80%）。上述指标经统计学处理差异均有显著性,治疗组优于对照组（P〈0.05）。结论中医辨证结合西医分期治疗急性脑梗死有较为明显的疗效优势。

Clinical Trial on Treatment of Acute Cerebral Infarction with TCM Treatment According to Syndrome Differentiation Combining Western Medicine by Staging

OBJECTIVE: To observe the curative effect of integrated Chinese and Western medicine on acute cerebral infarction (ACI). METHODS: Two hundred and seventy-nine ACI patients were assigned to two groups. The control group (140 cases) was treated with Western medicine by staging and the treated group (139 cases) was given TCM therapy according to syndrome differentiation on the basis of Western medicine. The end point was set at the 90th day of the administration. The curative effect was assessed by Chinese stroke scale (CSS), National Institutes of health stroke scale score (NIHSS), Rankin scale and Barthel index (BI). RESULTS: At the end point of the trial, the total effective rate was 73.38% in the treated group and 61.43% in the control group, the former was superior to the latter (P<0.05). There were 66 cases (47.14%) in the control group and 80 cases (57.55%) in the treated group with improvement rate of NIHSS > or =40%, 65 cases (46.43%) with their Rankin scale within 0-2 grade in the control group and 78 cases (56.12%) in the treated group, 60 cases (42.86%) in the control group and 71 cases (51.08%) in the treated group with BI > or =85, 61 cases (43.57%) in the control group and 72 cases (51.80%) in the treated group with improvement rate of CSS > or = 46%, comparison between them showed significant differences (P < 0.05). CONCLUSION: TCM therapy accord-ing to syndrome differentiation combined with Western medicine by staging shows better curative efficacy on ACI.