2型糖尿病合并高血压与血清某些元素的相关性分析

目的探讨2型糖尿病(Type 2 diabetes mellitus,T2DM)合并高血压发病与血清各元素水平的相关性,为控制T2DM病情提供更科学、更合理的依据。方法选取2015年3月至2016年5月乌鲁木齐市某三甲医院住院的1024例T2DM患者,将T2DM患者按照有无合并高血压分为T2DM合并高血压组和T2DM无合并高血压组,分析两组患者血清中的各元素水平及其与T2DM合并高血压发病之间的相关性。结果1024例T2DM患者中,627例合并高血压,占61.20%;397例患者无高血压,占38.80%;T2DM合并高血压组和T2DM无合并高血压组血清钠、镁水平之间差异有统计学意义(P<0.05);血清钠、镁水平与T2DM合并高血压正相关(P<0.05);血清钠水平的升高,血清镁水平的下降为T2DM合并高血压发病的相关因素。结论血清钠、镁水平与T2DM合并高血压发病呈正相关。血清钠水平的升高、镁水平的下降为T2DM合并高血压发病的相关因素。提示患者血清中各元素水平的差异在糖尿病病变的发生发展中具有一定的作用。

Correlation analysis between type 2 diabetes mellitus with hypertension and certain serum elements levels

Objective To investigate the correlation between the incidence of type 2 diabetes mellitus(T2DM)with hypertension and the levels of some elements in serum,and to provide a more scientific and reasonable basis for the control of T2DM.Methods A total of 1024 T2DM patients admitted to a top three hospital in Urumqi from March 2015 to May 2016 were selected.Patients with T2DM were divided into T2DM with hypertension group and T2DM without hypertension group according to the presence or absence of hypertension.Various elements levels in the serum were analyzed.The correlation between serum levels and the incidence of hypertension with T2DM was analyzed,and the related risk factors were explored by using logistic regression.Results Among 1024 T2DM patients,627 patients had hypertension,accounting for 61.20%,while 397 patients had no hypertension,accounting for 38.80%.There was a positive correlation between serum sodium and magnesium levels with T2DM in hypertension(P<0.05).The increase of serum sodium level and the decrease of magnesium level were the risk factors of T2DM with hypertension.This result suggested that the difference of serum levels of various elements may play a role in the occurrence and the development of T2DM.Conclusions Serum sodium and magnesium levels were positively correlated with the incidence of T2DM with hypertension.The increase of serum sodium level and the decrease of magnesium level were influencing factors of the incidence of T2DM with hypertension.This study suggests that the serum levels of sodium and magnesium play a role in the occurrence and development of T2DM.