吲哚菁绿荧光显像在腹腔镜解剖性肝切除术中的应用

目的探讨吲哚菁绿(indocyanine green,ICG)荧光显像在腹腔镜解剖性肝切除术(laparoscope anatomical hepatectomy,LAH)中的临床应用价值。方法回顾性分析2018年1月至2019年12月在郑州大学人民医院(河南省人民医院)行LAH的85例原发性肝癌病人的临床资料。其中43例行常规LAH(对照组),42例在吲哚菁绿荧光显像指导下行LAH(观察组)。比较两组病人术中术后相关指标。结果对照组和观察组在年龄、性别、肝功能储备、手术切除范围、手术时间、术后病理、术后肝功能、术后并发症发生及随访结果比较,差异均无统计学意义(均P>0.05)。与对照组相比,观察组术中出血量减少,术后C反应蛋白峰值降低,术后住院时间减少,差异均有统计学意义(均P<0.05)。结论ICG荧光显像指导LAH是一种安全有效的手术方法,值得推广应用。

Application of indocyanine green fluorescence imaging in laparoscope anatomical hepatectomy

Objective To investigae the clinical application value of indocyanine green fluorescence imaging in laparoscopic anatomical hepatectomy(LAH).Methods The clinical data of 85 patients with primary liver cancer who underwent LAH in People′s Hospital of Zhengzhou University(Henan Provincial People′s Hospital)from Jan.2018 to Dec.2019 were retrospectively analyze.Among them,43 patients received routine LAH(control group)and 42 patients were under the guidance of indocyanine green(ICG)fluorescence imaging to operate the LAH(observation group).Intraoperative and postoperative indicators the two groups were compared and analyzed.Results There was no statistically significant difference between the control group and the observation group in age,gender,liver function,surgical resection range,operation time,postoperative pathology,postoperative liver function,postoperative complications and follow-up results(P>0.05).Compared with the control group,intraoperative blood loss,postoperative CRP level and postoperative length of hospital stay in the observation group were significantly reduced,and the differences have statistically significance(P<0.05).Conclusion ICG fluorescence imaging in LAH is a safe andeffective surgical method,which is worthy of promotion clinically.