Beobachtungen zum Mechanismus der Nenitzescu-Reaktion Synthese von 6-Hydroxy-indol-Derivaten

Synthesis of 6-Hydroxyindoles Reaction of p-benzoquinone (1) with 13 substituted β-arylaminocrotonates 2 in propionic acid yields 6-hydroxy-indoles 5 . By-products are: 5-hydroxyindoles 3 , 5-acyloxy-4-hydroxyindoles 4 and arylaminobenzofurans 6 as new products. The structures of the furans 6 were clarified by chemical and spectroscopical methods. The reaction path that leads to 6-hydroxyindols is discussed.