| 原发性高血压患者血清1,25二羟维生素D水平的相关性研究 |
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| 引用本文： | 刘翀,韦铁民,曾春来.原发性高血压患者血清1,25二羟维生素D水平的相关性研究[J].心脑血管病防治,2011,11(3):182-183,186,I0002. |
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| 作者姓名： | 刘翀 韦铁民 曾春来 |
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| 作者单位： | 温州医学院附属第五临床医院,丽水市中心医院心内科,浙江,丽水,323000 |
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| 摘 要： | 目的:探讨原发性高血压患者血清1,25二羟维生素D水平与健康人群的差异,及可能影响1,25二羟维生素D水平的因素。方法 :随机选取原发性高血压患者124例(高血压组)与血压正常的健康人58例(对照组),进行血肌酐、血清1,25-二羟维生素D、肾素、钙离子水平测定和对比分析。结果 :与对照组比较,高血压组的血肌酐水平显著升高(81.91±30.75)μmol/L比(76.53±11.77)μmol/L]及肾素(3.14±9.22)ng/ml.h比(0.43±0.22)ng/ml.h],差异具有统计学意义(均P<0.01),1,25-二羟维生素D水平降低(38.72±8.02)pg/ml比(39.59±11.53)pg/ml],差异具有统计学意义(P<0.05)。两组的钙离子浓度无差异。Pearson分析显示血肌酐水平与血清1,25-二羟维生素D水平存在负相关(r=-0.15,P<0.05)。结论 :高血压患者的1,25二羟维生素D水平显著低于健康人群。
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| 关 键 词： | 原发性高血压 1 25二羟维生素D 肌酐 |
A Study on Serum 1,25(OH)2-vitamin D Level in Patients with Primary Hypertension. |
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| LIU Chong,WEI Tie-min,ZENG Chun-lai.A Study on Serum 1,25(OH)2-vitamin D Level in Patients with Primary Hypertension.[J].Prevention and Treatment of Cardio_Cerebral_Vascular Disease,2011,11(3):182-183,186,I0002. |
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| Authors: | LIU Chong WEI Tie-min ZENG Chun-lai |
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| Institution: | LIU Chong,WEI Tie-min,ZENG Chun-lai.Department of Cardiology,Lishui Central Hospital and the Fifth Affiliated Hospital of Wenzhou Medical College,Zhejiang 323000,China |
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| Abstract: | Objective To investigate the differences of serum 1,25(OH)2-vitamin D level between primary hypertension patients and healthy population and to explore the factors which may affect the 1,25(OH)2-vitamin D level.Methods 124 patients randomly selected with primary hypertension were classified as hyprtension group,58 healthy volunteers with normal blood pressure were classified as control group.The Serum creatinine,serum 1,25(OH)2-vitamin D,renin,calcium ion levels were measured and compared between the two gr... |
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| Keywords: | Primary hypertension 1 25(OH)2-vitamin D Creatinine |
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