用血清学方法预测杭州市区风疹局部暴发的研究

1987年我们用酶免疫试验（Rubazyme-M药盒）和HI试验证实杭州市各区均有风疹暴发，结合前几年人群风疹免疫监测结果，预测最近两年仍将有风疹流行。用市售Rubazyme－M药盒检测风疹IgM抗体，检出率以疹后5－14天。酶免疫法与HI法诊断风疹的符合率为90．3％，酶标的漏诊率为9．7％。此外本文还对风疹与麻疹鉴别的重要性及HI试验诊断风疹的指标作了讨论。

Study on Forecasting Local Rubella Outbreaks in Hangzhou City Proper by Serologic Method

Rubella outbreaks were proved by the rubazyme M test (Abbott) and rubella haemagglutination inhibition test in Hangzhou city in 1987. On the basis of these and previous immune surveillance in human population, we predict that epidemic of rubella will also occur in recent two years. Rubella IgM antibody was detected by enzyme immunoassay using commercially available Rubazyme-M Diagnostic Kit (Abbott Laboratories). It was detected within 0-66 days after eruption and detection rate was the highest between 5th and 14th day of onset. The coincidence rate of enzyme immunoassay and HAI tests for rubella diagnosis was 90.3%, and false negative rate of enzyme immunoassay was 9.7%. Besides, the importance of differentiating measles from rubella and diagnostic criteria of HAI test for rubella were discussed.