角膜内皮炎共焦显微镜形态学分析

目的:观察角膜内皮炎的共焦显微镜下形态学特征。方法:应用Confoscan 4.0共焦显微镜对24例24眼角膜内皮炎患者的角膜进行扫描检查,记录并分析各层角膜图像。结果:所有患者前部基质混浊,角膜深基质层可见基质细胞排列紊乱及条索状高反光结构,深基质层中还可见低反光带为后弹力层皱褶,角膜内皮细胞前可见斑片状大小不等的高反光结构,病变区角膜内皮细胞水肿、变性呈无结构暗区,内皮细胞呈多形性改变。4眼角膜上皮细胞边界不清,排列疏松,细胞较大,细胞核呈高反光结构,其中可见泡状暗区。结论:共焦显微镜可活体检查角膜内皮炎患者角膜组织各层结构,起到类似病理组织切片的作用;角膜内皮炎以深基质层及内皮细胞层损害为特征;共焦显微镜检查对角膜内皮炎具有一定的参考价值。

Analysis of the morphology of corneal endotheliitis by confocal microscope

AIM:To observe the morphology of corneal endotheliitis by confocal microscope.METHODS: Confoscan 4.0 (made in Japan) was used to scan the 24 cases 24 eyes suffered from corneal endotheliitis and the image of every corneal sheet was recorded.RESULTS: Opacitas were found in anterior stroma.In deeper stroma, stroma cell was disorder and high glisten structure and DM reductus were found. High glisten structure were found before corneal endothelium which suggested that pleomorphism transform in corneal endothelium. There were corneal epithelium cell degeneration in 4 eyes.CONCLUSION: By confocal microscope we can observe the morphology of every corneal sheet as well as histopathologic slide. The morphological characteristic of corneal endotheliitis is that the deeper stroma and endothelium are damaged. Confocal microscope has certain reference value for cormeal endothelitis.