| 竹叶提取液对小鼠移植性肿瘤生长的抑制作用 |
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| 引用本文： | 李映红,刘红梅,严银钫,罗德生,郑红花,王梅娟,姚旌旗. 竹叶提取液对小鼠移植性肿瘤生长的抑制作用[J]. 湖北中医药大学学报, 2002, 4(4): 17-19 |
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| 作者姓名： | 李映红 刘红梅 严银钫 罗德生 郑红花 王梅娟 姚旌旗 |
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| 作者单位： | [1]咸宁医学院生物化学教研室437100 [2]武汉大学医学院病毒研究所430071 |
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| 基金项目： | 湖北省教育厅重点科研基金(项目编号:98A075) |
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| 摘 要： | 目的：探讨竹叶提取液对小鼠移植性肿瘤生长的抑制作用及对免疫功能的影响。方法：观察不同剂量竹叶取液对接种H22－肝癌细胞的小鼠的肿瘤生长和单核巨噬细胞功能的影响，检测小鼠胸腺指数、脾指数的变化。结果：与对照组相比，大、中剂量实验组动物瘤重明显减轻，单核巨噬功能显增强，胸腺（脾）指数显提高（P＜0．05）。结论：竹叶提取液对小鼠移植性肿瘤有明显的抑制作用。
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| 关 键 词： | 竹叶提取液 小鼠 移植性肿瘤 抑制作用 |
| 文章编号： | 1008-987X(2002)04-0017-03 |
| 修稿时间： | 2002-08-26 |
INHIBITION OF BLE ON GROWTH OF TRANSPLANTED TUMOR IN MICE |
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| Li Yinghong,Liu Hongmei,Yan Yinfang,et al. INHIBITION OF BLE ON GROWTH OF TRANSPLANTED TUMOR IN MICE[J]. Journal of Hubei University of Chinese Medicine, 2002, 4(4): 17-19 |
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| Authors: | Li Yinghong Liu Hongmei Yan Yinfang et al |
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| Affiliation: | Li Yinghong,Liu Hongmei,Yan Yinfang,et al Department of Biochemistry,Xianning Medical College,Hubei Xianning 437100 |
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| Abstract: | To explore the inhibtion of bamboo leaf extract (BLE) on growth of transplanted H^ cancer in mice and the effect of BLE on mice immunological function. Methods: The effect of aniso-dosage BLE on growth of tumour in mice inoculated H22 -Hepatocarcinoma cell and function of mono-nucleus histocyte were observed. The size of the transplanted tumor and exponent of thymus as well as spleen were detected after treated with BLE for three weeks. Results: Comparing with the control group, the size and weight of tumor in high or middle-dose experiment groups decreased obviously, while the function of mono-nucleus histocyte was enhanced significantly, and the exponents of thymus and spleen came to increase nota-bly(P<0.05). Conclusion: The results indicated that BLE can show a satisfactory function of inhibiting transplanted tumor growth. |
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| Keywords: | Bamboo leaf extract (BLE) Tumor Inhibition Immunity |
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