| 自身免疫性甲状腺疾病甲状腺单个核细胞活化抗原的表达 |
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| 引用本文： | 王坚. 自身免疫性甲状腺疾病甲状腺单个核细胞活化抗原的表达[J]. 医学争鸣, 1992, 13(2): 142-145 |
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| 作者姓名： | 王坚 |
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| 作者单位： | 南京军医总医院内分泌科，西京医院内分泌科，第四军医大学病理学教研室，第四军医大学免疫学教研室，第四军医大学病理学教研室 研究生，南京 210002 |
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| 摘 要： |
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| 关 键 词： | 甲状腺疾病 自身免疫 免疫组织化学 |
T- activation antigens expression on thyroid mononuclear cells in autoimmune thyroid diseases |
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| WANG Jian HU Shao -Wen,WANG Bo-Yun,JIN Bo-Quan and HUANG Gao-Sheng. T- activation antigens expression on thyroid mononuclear cells in autoimmune thyroid diseases[J]. Negative, 1992, 13(2): 142-145 |
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| Authors: | WANG Jian HU Shao -Wen WANG Bo-Yun JIN Bo-Quan HUANG Gao-Sheng |
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| Affiliation: | WANG Jian HU Shao -Wen,WANG Bo-Yun,JIN Bo-Quan and HUANG Gao-Sheng Department of Endocrinology,Xijing Hospital Department of Pathology Department of Immunology |
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| Abstract: | The authors investigated in situ the expression of a group of T-activation antigens on thyroid gland mononuclear cells (TG-MNC) in autoimmune thyroid diseases by APAAP immunohistochemical technique. A total number of 40 specimens were used. It is shown that the positive rates of all the four activation antigens in TG-MNC are significantly higher in Hashimoto's thyroiditis (HT)than in nontoxic goiter (P<0.05 -0.01). However, the differences between HT and Graves' disease are insignificant (P>0-05) except the one of HLA-DR antigens. The activation-antigen-positive (especially TUSA1+ ) MNC is often seen intruding into thyroid lumens of HT. |
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| Keywords: | thyroid diseases autoimmunity immunohistochemistry |
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