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| 18F-FDG PET/CT结合胸部屏气螺旋CT扫描对非小细胞肺癌术前T分期的价值 | |
| 引用本文： | 李蒙,吴宁,郑容,刘瑛,梁颖,张雯杰,赵平. 18F-FDG PET/CT结合胸部屏气螺旋CT扫描对非小细胞肺癌术前T分期的价值[J]. 中国医学影像技术, 2010, 26(1): 5-9 |
| 作者姓名： | 李蒙 吴宁 郑容 刘瑛 梁颖 张雯杰 赵平 |
| 作者单位： | 1. 中国医学科学院,北京协和医学院,肿瘤医院影像诊断科,北京,100021 2. 中国医学科学院,北京协和医学院,肿瘤医院影像诊断科,北京,100021;中国医学科学院,北京协和医学院,PET/CT中心,北京,100021 3. 中国医学科学院,北京协和医学院,PET/CT中心,北京,100021 4. 中国医学科学院,北京协和医学院,PET/CT中心,北京,100021;中国医学科学院,北京协和医学院,腹部外科,北京,100021 |
| 基金项目： | "十一五"国家科技支撑计划课题，"十一五"新药专项支持 |
| 摘 要： | 目的 探讨~(18)F-FDG PET/CT结合胸部屏气螺旋CT扫描在非小细胞肺癌(NSCLC)患者术前T分期方面的应用价值.方法 90例经手术病理证实的NSCLC患者均于原发肿瘤切除术前行~(18)F-FDG PET/CT和胸部屏气螺旋CT扫描,由两名有PET/CT诊断经验的影像医师采用双盲法分别根据屏气CT和PET/CT图像对肿瘤行T分期.以手术病理结果作为金标准,对CT和PET/CT的分期结果进行比较.T分期参照美国癌症联合会(AJCC)修订的第7版肿瘤分期手册标准.结果 以手术病理分期为金标准,CT正确分期69例,PET/CT正确分期75例,CT及PET/CT的符合率分别为75.56%和82.22%,差异有统计学意义(P=0.03).8例为中央型肺癌合并肺不张,CT正确分期3例,PET/CT正确分期6例;5例同侧肺内转移,CT正确诊断2例,PET/CT正确诊断4例.结论 胸部屏气螺旋CT扫描能很好地显示NSCLC原发肿瘤的形态、大小和侵犯范围,是判断T分期的主要方法.~(18)F-FDG PET/CT在区分中央型肺癌与肺不张、诊断肺内转移等方面较单独CT检查具有优势. |
| 关 键 词： | 肺肿瘤 肿瘤分期 体层摄影术,发射型计算机 体层摄影术,X线计算机 18F氟脱氧葡萄糖 |
| 收稿时间： | 2009-09-18 |
| 修稿时间： | 2009-10-06 |
18F-FDG PET/CT combining chest breath-hold spiral CT in the presurgical T staging of non-small cell lung cancer |
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| LI Meng,WU Ning,ZHENG Rong,LIU Ying,LIANG Ying,ZHANG Wen-jie and ZHAO Ping. 18F-FDG PET/CT combining chest breath-hold spiral CT in the presurgical T staging of non-small cell lung cancer[J]. Chinese Journal of Medical Imaging Technology, 2010, 26(1): 5-9 | |
| Authors: | LI Meng WU Ning ZHENG Rong LIU Ying LIANG Ying ZHANG Wen-jie ZHAO Ping |
| Affiliation: | Department of Diagnostic Imaging, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China;Department of Diagnostic Imaging, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China;PET/CT Center, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China;PET/CT Center, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China;Department of Diagnostic Imaging, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China;PET/CT Center, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China;PET/CT Center, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China;PET/CT Center, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China;PET/CT Center,;Department of Abdominal Surgery, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China |
| Abstract: | Objective To assess the diagnostic value of 18 F-FDG PET/CT combining chest breath-hold spiral CT in preoperative primary tumor staging(T stage)of non-small lung cell cancer(NSCLC)before operation.Methods Ninety NSCLC patients underwent curative surgical resection after integrated 18 F-FDG PET/CT and chest breath-hold spiral CT examination.Two experienced radiologists blindedly staged all primary tumors in consensus by CT and PET/CT images.Surgical and histopathologic results served as the golden standard f... |
| Keywords: | Lung neoplasms Neoplasm staging Tomography emission-computed Tomography,X-ray computed Fluorodeoxyglucose F18 |
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