| Abstract: | Objective To evaluate ifKDIGO (kidney disease: improving global outcomes) criteria for short?term prognosis of cardiorenal syndrome type I was superior to RIFLE (risk, injury, failure, loss of kidney function, end?stage kidney disease) and AKIN (the acute kidney injury network) criteria. Methods Data was retrospectively collected from patients with acute heart failure in Guangdong General Hospital between July 2005 and July 2012. The in?hospital mortality was regarded as outcome measures. Baseline serum creatinine was defined as first serum creatinine on admission. Kaplan?Meier curve was used to evaluate in?hospital survival by three AKI criteria and AKI by KDIGO but not RIFLE or AKIN in patients with cardiorenal syndrome type I. Cox regression was used for multivariate analysis of in?hospital mortality. Results Among 732 patients, 154 cases (21%) were diagnosed as AKI by KDIGO instead of RIFLE or AKIN. Incidence for the cardiorenal syndrome type I by KDIGO, RIFLE and AKIN were significantly different (54.7% vs. 38.6%, 54.7% vs 50.1%, P＜0.001).Kaplan?Meier curve showed that in?hospital survival rates of patients with AKI diagnosed by KDIGO but not RIFLE or AKIN are lower than those without AKI (Log rank P=0.011). Cox regression indicated that AKI by KDIGO but not RIFLE or AKIN was an independent risk factor of in?hospital mortality (P=0.008). Conclusion KDIGO criteria is superior to RIFLE and AKIN criteria on predicting in?hospital mortality of cardiorenal syndrome type I. |
