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Extracorporal blood purification for acute poisoning

??Abstract??The treatment of acute poisoning has always been a challenge in modern medicine??because there are so many types of poisonous materials and the poisoning individual varies??and the detoxification drugs with special effects are lacking.Extracorporal blood purification has an established role in the treatment of various intoxications.Hemoperfusion??hemodialysis??hemofiltration and plasmapheresis are effective methods for removal of toxin from the body and usually applied in selected cases of diagnosed severe forms as the options of fast elimination of the intoxicating agent.With the improvement of blood purification techniques and new life supporting systems??their clinical applications are rapidly increasing in number and scope.These methods have been applied whenever certain potentially lethal intoxications are diagnosed and/or suspected??even without evidence of life impediment at the time of institution of therapy.However??the large and high quality controlled trials are needed to prove the clear elimination of each type of intoxication by extracorporal blood purification techniques.