介入性宫内干预后绒毛膜羊膜分离的临床分析

目的：探讨介入性宫内干预后出现绒毛膜羊膜分离的临床特点及高危因素。方法：回顾性分析中山大学附属第一医院胎儿中心2001年7月—2010年6月行介入性宫内干预术后超声检查发现绒毛膜羊膜分离的病例，介入性干预包括羊水减量术213例、宫内输血28例、电凝脐带术28例。结果：269例宫内干预术后的病例中，共发现9例绒毛膜羊膜分离，羊水减量术后4例（4/213，1.88%），宫内输血术后1例（1/28，3.6%），电凝脐带术后4例（4/28，14.3%）。结论：电凝脐带术后绒毛膜羊膜分离发生率高，双胎输血综合征及羊水过多可能是绒毛膜羊膜分离发生的高危因素。

Chorioamniotic Membrane Separation after Invasive Intrauterine Intervene

Objective：To investigate the clinical characteristics of the chorioamniotic membrane separation （CMS） afterinvasive intrauterine treatment. Methods：Retrospective review of a maternal population undergoing intra uterine therapy at a single center following the postoperative ultrasound to follow-up for membrane separation. The intrauterine procedures consisted of cord coagulation reduction，amnioreduction，intrauterine transfusion in Center of Fetal，the First Affiliated Hospital of Sun Yat-sen University from 2001 July to 2010 June. Results：From 2001 to 2010，we found 9 cases of CMS in 269 cases after invasive procedure. 4 cases（4/213，1.88%） had amnioreduction，1 case（1/28，3.6%） had intrauterine transfusion and 4 cases（4/28，14.3%）had cord coagulation reduction. Conclusions：There was a higher risk of CMS after fetoscopic cord coagulation reduction.