脑卒中急性期抑郁焦虑障碍多因素分析

目的研究脑卒中急性期抑郁焦虑障碍的发生情况及其相关因素.方法采用脑血管病诊断标准、CCMD-3诊断标准中关于脑器质性精神障碍的诊断标准以及相关量表(SDS、SAS、HAMD、HAMA、DNF、ADL和伴发疾病量表)和一般情况调查表,对109例观察对象调查、评估和诊断.根据诊断分组,并比较分析脑卒中急性期抑郁焦虑的相关因素.结果脑卒中急性期抑郁焦虑障碍51例(46.79%),相关性因素有既往情感障碍病史或家族史、内向个性与神经功能缺损程度、日常生活能力、伴发疾病、家庭关系及近期负性生活事件等7个因素.结论脑卒中急性期情感障碍因素,主要为生物学因素和社会心理学因素两大类.

A Multiple Factor Analysis for Depression and Anxiety in the Acute Phase of Cerebral Apoplexy

Objective To study the rate of incidence and relevant factors of the acute-onset affective disorders of depression and anxiety in cerebral apoplexy.Methods 109 patients suffering from cerebral apoplexy were investigated, assessed and diagnosed with two criteria for organic mental diseases (one for cerebral vascular disease,and the other for CCMD-3) and correlative scales and self-designed questionnaire. According to the diagnosis they were divided into two groups: The first group was patients without affective disorders (n=58) and the second with affective disorders(n=51).The relevant factors were analyzed by different statistical methods.Results The total incidence rate of the affective disorders in acute phase of cerebral apoplexy was 46.79%.The disorders included depression 39.45% and anxiety 17.43%.The relevant factors included depression history or family history, the degree of neurological deficit, accompanying disease, daily living activity, the relationship with family members, personality and recent negative living events.Conclusion The high incidence of affective disorders in the acute phase of Cerebral Apoplexy is the result of multiple factors mainly including biologic, psychological and social factors.