| 中医药黄酮类化合物的抗宫颈癌作用机理研究进展 |
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| 引用本文： | 米合勒阿衣·艾克帕,艾斯克尔·吐拉洪,阿不都热依木·玉苏甫.中医药黄酮类化合物的抗宫颈癌作用机理研究进展[J].中国民族民间医药杂志,2014(12):14-15. |
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| 作者姓名： | 米合勒阿衣·艾克帕 艾斯克尔·吐拉洪 阿不都热依木·玉苏甫 |
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| 作者单位： | 新疆医科大学维吾尔医学院,新疆乌鲁木齐830011 |
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| 基金项目： | 新疆维吾尔自治区科技厅自然基金青年项目,异常黑胆质成熟剂总黄酮对人宫颈癌Hela细胞侵袭的影响及其机制研,项目编号：2013211B47. |
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| 摘 要： | 文章在查阅国内外相关文献的基础上,对中医药黄酮类化合物抗宫颈癌作用机制的研究进展综述。中医药黄酮类化合物抗人宫颈癌的作用机制主要有抑制宫颈癌细胞增殖及促进其凋亡、调节信号传导,抑制肿瘤细胞的侵袭和转移能力、逆转Hela细胞株多药耐药性,免疫增强作用,能够增强抗氧化能力和清除自由基的能力。对中医药抗宫颈癌作用机制的研究,阐明其物质基础以及将为开发更安全有效的抗宫颈癌新药提供新的思路。
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| 关 键 词： | 中医药黄酮类化合物 宫颈癌 作用机制 |
Research summary of mechanism s of the Flavonids of Chinese herbal medicine against cervical neoplasms |
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| Institution: | Mikray. Akpar Askar. Turahun Abduriyim. Yusup( Inistitute of Traditional Uygur Medicine, Xinjiang Medical University, Urumqi 830011, China) |
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| Abstract: | Based on the related literature at home and abroad, we reviewed research progress of the mechanisms of Flavonids of Chinese herbal medicine against human cervical neoplasms. The mechanisms of the Flavonids of Chinese herbal medicine against human cervical neoplasms mainly includes inducing Inhibition of cancer cell proliferation and induce apoptosis, Regulate signal transduction, inhibiting the ability of invasion and mestasis. Reverse Hela cell muhidrug resistance, Immune enhancement, Enhanced antioxidant capacity and free radical scavenging ability. 1 Researches on the mechanisms of Flavonids of Chinese herbal medicine against human cervical neoplasms will provide new ideas for developing new safer and mole elective anticancer drugs. |
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| Keywords: | Flavonids of Chinese herbal medicine Cervical neoplasms Mechanism |
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