273例脑性瘫痪患儿临床资料回顾性分析

目的分析273例脑性瘫痪患儿的临床资料,以明确脑性瘫痪发生的高危因素、临床表现特点以及并发症等情况,以便对脑瘫高危儿进行早期诊断、早期干预,以进一步改善其预后以及提高生活质量。方法对273例脑瘫患儿的临床资料进行回顾性分析,包括高危因素、头颅CT和磁共振成像(MRI)、脑电图改变以及伴发病的情况进行分析。结果 273例患儿以痉挛型54.2%最多见,其次为肌张力低下型14.3%和混合型13.9%,强直型最少见0.7%。围产期高危因素主要为高胆红素血症42.5%、新生儿窒息35.9%、早产27.5%、低出生体重32.6%;250例脑性瘫痪共计有500余种围生期高危因素,每个患儿平均大于2个高危因素。头颅CT或头颅MRI异常率达90.4%,脑电图异常率37.4%。伴发疾病异常率为78.8%,其中以语言障碍及智力低下最多见,分别为67.0%、64.7%,癫痫为20.5%,视觉障碍最少5.6%。结论进一步证实了脑性瘫痪的发生与围生期高危因素密切相关。脑性瘫痪患儿头颅影像学及脑电图检查的异常率较高,对脑性瘫痪及癫痫的病因及预后可能有提示作用。脑性瘫痪患儿多合并语言障碍、智力低下、癫痫等并发病。

CORRELATION ANALYSIS OF THE CLINICAL DATA OF 273 CASES OF CHILDREN WITH CEREBRAL PALSY

Objective To search for ways to reduce the incidence rate of cerebral palsy by analysis of the causes and clinical features of cerebral palsy and the assistance examination results. MethodsThe clinical data of 273 cases of children with cerebral palsy were analyzed retrospectively,with priority analyses of the causes,clinical types,electroencephalogram(EEG) and skull CT,skull MRI. ResultsAmong the clinical types for the 273 children with CP,54.2% were With spastic cerebral palsy,14.3% were Hypotonia cerebral palsy.The analysis suggested that newborn bilirubin encephalopathy(42.5%),premature(27.5%),low birth weight(32.6%) and neonatal asphyxia(35.9%).The research also showed that the abnormal rate of the skull CT was 90.4%% while,the EEG was 37.4%.The abnormal rate of Concomitant diseases was 78.8%.The abnormal rate of language disorders and hypophrenia were 67.0% and 64.7%. ConclusionFurther confirmed the occurrence of cerebral palsy and perinatal risk factors were closely related.The abnormal rates of brain CT or MRI and EEG electroencephalogram are higher in children with CP,which was helpful in determining the etiology and prognosis of CP.