Cyst‐like cerebral lesions in tuberous sclerosis |
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| Authors: | Beate Lemcke Martin Zenker Walter Huk Jürgen Horst Karin Mayer |
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| Institution: | 1. Institute of Human Genetics, University of Münster, Münster, Germany;2. Department of Pediatrics, University of Erlangen‐Nuremberg, Erlangen, Germany;3. Department of Neuroradiology, University of Erlangen‐Nuremberg, Erlangen, Germany;4. Institute of Human Genetics, University of Erlangen‐Nuremberg, Erlangen, Germany |
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| Abstract: | Known brain manifestations of tuberous sclerosis (TSC) are cortical sclerotic tubera, giant cell astrocytomas, subependymal calcified nodules in the lateral walls of the lateral ventricles, and white matter heterotopias. In addition, small cyst‐like lesions in the white matter have been described. We report on three TSC patients with hitherto undescribed large cyst‐like cerebral lesions in subcortical and white matter locations. We emphasize that cystoid brain degeneration is a rare but typical cerebral manifestation of TSC and suggest that, in patients with such lesions, TSC should be taken into consideration. © 2002 Wiley‐Liss, Inc. |
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| Keywords: | tuberous sclerosis TSC cerebral cysts brain cysts magnetic resonance imaging |
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