妊娠期高浓度血红蛋白对妊娠结局的影响

妊娠期母体血液系统发生一系列生理变化以适应胎儿生长发育,血液总容量增加并有一定程度的血液稀释。如果妊娠期血液不能有效稀释,血红蛋白浓度过高,会引起血液黏度增加,全身血液循环不能适应子宫-胎盘血流的需要。其结果可能导致子宫-胎盘血流量减少、减慢,而引起子宫胎盘缺血缺氧、血管痉挛、血压升高等,而发生妊娠期高血压疾病、小于胎龄儿、早产、低出生体质量、妊娠期糖尿病、死产等。综述妊娠期高浓度血红蛋白对不良妊娠结局的影响,以引起对妊娠期高浓度血红蛋白的重视。

Effects of High Maternal Hemoglobin Concentrations During Gestation on the Pregnancy Outcomes

Maternal hematological system happens to have a series of physiological changes such as plasma volume expansion and hemodilution to adapt to the growth of the fetus during normal pregnancy.In contrast,high maternal hemoglobin concentrations usually coincide with hemo concentration and over activation of blood coagulation both of which alter blood rheology and result in adverse outcome of pregnancy such as hypertensive disorders in pregnancy,small for gestational age,premature birth,low birth weight gestatio...