麻醉诱导期应用右美托咪定预防小儿七氟醚麻醉苏醒期躁动的意义

目的：探讨右美托咪啶在预防小儿七氟醚麻醉苏醒期躁动中的应用价值。方法：将60例行腹股沟斜疝修补术的患儿随机分为右美托咪定组和生理盐水组各30例，两组患儿均接受七氟醚吸入性麻醉，右美托咪定组患儿在麻醉诱导后静脉注射0.5 μg/kg右美托咪定，生理盐水组患儿在麻醉诱导后静脉注射等体积生理盐水，比较两组患儿的麻醉苏醒时间、拔管时间及躁动发生情况。结果：右美托咪定组患儿的苏醒时间、拔管时间均长于生理盐水组（P均<0.01）；右美托咪定组患儿的躁动发生率为13.3%，低于生理盐水组的40.0%（P<0.05）。结论：诱导期应用右美托咪定能够显著抑制小儿七氟醚麻醉苏醒期躁动的发生，但会延长患儿的苏醒时间及拔管时间。

Significance of Dexmedetomidine in Prevention of Sevoflurane Anesthesia in Children during Anesthesia Induction Period

Objective: To explore the application value of dexmedetomidine in prevention of sevoflurane anesthesia in children during anesthesia induction period. Methods: Totally 60 children undergoing indirect inguinal hernia hernioplasty were randomly extracted to be divided into the dexmedetomidine group and the saline group, with 30 cases in each group. Both groups received sevoflurane inhalation anesthesia. The dexmedetomidine group was given intravenous injection of 0.5 g/kg dexmedetomidine after anesthesia induction, and the saline group was treated with intravenous injection of equal volume saline after anesthesia induction. The anesthesia recovery time, extubation time and agitation of two groups were compared. Results: The recovery time and extubation time of the dexmedetomidine group were longer than those of the saline group (P<0.01). The incidence of agitation in the dexmedetomidine group was 13.3%, lower than that in the saline group (40.0%, P<0.05). Conclusion: The application of dexmedetomidine in the induction period can significantly inhibit the occurrence of agitation in children with sevoflurane anesthesia, but it will prolong the recovery time and extubation time of children.