某院抽动障碍患儿用药依从性及影响因素分析

目的:分析抽动障碍(TD)患儿的用药依从性和影响因素,为提高治疗效果提供参考。方法:选择2015 年12 月至2016年12 月就诊于华西第二医院儿童神经科门诊的150 例TD 患儿,采用自行编制的问卷调查表收集数据,最终有效回收140 例患儿的问卷纳入研究。分别在患儿就诊3 个月和6 个月后,采用Morisky 量表电话随访用药依从性,运用有序多分类Logistic 回归模型分析影响用药依从性的因素。结果:140 例TD 患儿中,66 例(47.1%)3 个月依从性高,41 例(29.3%)6 个月依从性高。单因素分析显示,患儿用药依从性与居住地、有无共患病、药物类型、药物不良反应、治疗满意度、对疾病的了解程度、对药物用法的了解程度、是否接受患者教育、家庭月总收入有关(P 均<0.05)。有序多分类Logistic 回归分析显示,共患病、药物不良反应、 治疗满意度、是否接受患者教育和家庭月总收入对患儿用药依从性的影响有统计学意义(P 均<0.05)。结论:TD 患儿用药依从性不高,且随着服药时间延长而降低。用药依从性受多种因素影响,建议医院开展健康教育、提高服务水平、增进医患关系和建立用药依从性随访制度以提高患者的用药依从性。

Medication Compliance and Influencing Factors of Children with Tic Disorder in a Hospita

Objective: To analyze the medication compliance and influencing factors of children with tic disorder (TD) in West China Second Hospital, so as to provide reference for improving the treatment effects. Methods: Totally 150 children with TD admitted into West China Second Hospital from Dec. 2015 to Dec. 2016 were extracted. Data were collected by using self-made questionnaires. A questionnaire that effectively recovered 140 children was included in the study. After 3 months and 6 months of treatment, the Morisky scale was used to follow the medication compliance, and the multiple classification Logistic regression model was used to analyze the factors affecting medication compliance. Results: Of the 140 children with TD, 66 cases (47.1%) had good compliance for 3 months,and 41 cases (29.3%) had good compliance for 6 months. Univariate analysis showed that medication compliance was related to the residence, presence or absence of co-morbidity, type of medication, adverse drug reactions, treatment satisfaction, understanding of the disease, understanding of drug usage, presence or absence of education of the patient and monthly family income (P<0.05). Multiple classification Logistic regression model showed that the influence of co-morbidity, adverse drug reactions, treatment satisfaction, presence or absence of education of the patient and monthly family income on the medication compliance of children was statistically significant (P<0.05). Conclusion: The medication compliance of children with TD is not high, and it decreases with the prolonged medication time. Medication compliance is affected by many factors, and it is suggested that hospitals should carry out health education, improve service level, enhance doctor-patient relationship and establish the medication compliance follow-up system to improve patients''medication compliance.