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| 氯沙坦逆转高血压患者左室肥厚的临床研究 | |
| 引用本文： | 葛志明,季晓平,郝恩魁,刘科卫,李明. 氯沙坦逆转高血压患者左室肥厚的临床研究[J]. 山东大学学报(医学版), 2000, 38(2): 171-172 |
| 作者姓名： | 葛志明 季晓平 郝恩魁 刘科卫 李明 |
| 作者单位： | 1. 山东医科大学附属医院心内科 2. 青岛第二人民医院超声室 3. 济南军区总院心内科 4. 青岛铁路医院超声室 |
| 摘 要： | 目的探讨氯沙坦降低血压、逆转左室肥厚的临床价值。方法服用氯沙坦前后分别测量血压、应用超声心动图测定高血压患者的左心室厚度、重量和E／A比值。结果服药后血压、左室厚度和重量显著降低(P＜0.01)，左室舒张功能明显改善(P＜0.01)。结论氯沙坦能在降低血压的同时逆转左室肥厚，改善左室舒张功能。 |
| 关 键 词： | 高血压；肥厚，左心室；受体，血管紧张素；氯沙坦；超声心动图 |
| 文章编号： | 1000-0496(2000)02-0171-02 |
| 修稿时间： | 1999-07-23 |
CLINICAL STUDY ON REVERSION OF LEFT VENTRICULAR HYPERTROPHY BY LOSARTAN IN PATIENTS WITH ESSENTIAL HYPERTENSION |
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| GE Zhi-ming,JI Xiao-ping,HAO En-KUi. CLINICAL STUDY ON REVERSION OF LEFT VENTRICULAR HYPERTROPHY BY LOSARTAN IN PATIENTS WITH ESSENTIAL HYPERTENSION[J]. Journal of Shandong University:Health Sciences, 2000, 38(2): 171-172 | |
| Authors: | GE Zhi-ming JI Xiao-ping HAO En-KUi |
| Affiliation: | GE Zhi-ming,JI Xiao-ping,HAO En-KUi;(Dept.of Cardiology,the Affiliated hospital of Shandong Medical University) |
| Abstract: | Objective:To explore the clinical value of Losartan which may reduce blood pressure(BP)and reverse the left ventricular hypertrophy(LVH).Methods:The left ventricular thickness(LVI),mass(LVM)and E/A ratio measured respectively by echocardiography before and after the administration of Losartan in patients with essential hypertension.Results:BP,LVT and LVM remarkebly decreased (P<0.01),and E/A ratio significantly increased(P<0.01).Conclusion:Losartan can reverse LVH and improve left ventricular diastolic function while reducing BP. |
| Keywords: | Hpertension Hypertrophy,Left Ventriclulare Receptors,Angiotensin Losartan |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |