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Successful recovery of COVID-19-associated recurrent diarrhea and gastrointestinal hemorrhage using convalescent plasma
Authors:Li-Bo Zhang  Rong-Rong Pang  Qing-Hua Qiao  Zhi-Hua Wang  Xin-Yi Xia  Chang-Jun Wang  Xiao-Li Xu
Abstract:Background:Gastrointestinal symptoms are not rare among coronavirus disease 2019(COVID-19)patients,but there have been no reports regarding convalescent plasma therapy for the recovery of gastrointestinal problems in COVID-19 patients.Case presentation:We present two cases of patients with COVID-19-associated recurrent diarrhea and positive fecal occult blood who successfully recovered after a one-time convalescent plasma administration.Conclusion:When COVID-19 patients develop recurrent or refractory gastrointestinal symptoms and fail to respond to the available treatment,alternative therapy with convalescent plasma administration may be considered.
Keywords:Coronavirus disease 2019(COVID-19)  Convalescent plasma  SARS-CoV-2 virus  Gastrointestinal symptoms
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