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文拉法辛治疗抑郁障碍46例疗效分析
引用本文:黄学军,黄敏,龚梅恩,刘军,汤姿英.文拉法辛治疗抑郁障碍46例疗效分析[J].中国民康医学,2007,19(11):436-437.
作者姓名:黄学军  黄敏  龚梅恩  刘军  汤姿英
作者单位:1. 广州医学院第二附属医院,广东,广州,510260
2. 广州市药品检验所第8分所
摘    要:目的:观察文拉法辛治疗抑郁障碍的疗效及其不良反应。方法:应用该药治疗各种抑郁性障碍46例,疗程8周。用汉密尔顿抑郁量表(HAMD)、临床疗效总评量表的病情严重程度(CGI—S1)和副反应量表(TESS)评定疗效和不良反应。结果:文拉法辛总有效率为91.6%,临床痊愈率为48.6%。不良反应轻微。无一例因药物反应导致治疗中断。结论:文拉法辛治疗抑郁障碍疗效确切,不良反应轻微。值得临床医生在临床实践中做为一线抗抑郁药使用。

关 键 词:文拉法辛  抑郁障碍  疗效
文章编号:0369(2007)06-0436-02
修稿时间:2007-03-01

A study of venlafaxine in the treatment of depression
HUANG Xue -jun , HUANG Min, GONG Mei -en.A study of venlafaxine in the treatment of depression[J].medical journal of chinese peoples health,2007,19(11):436-437.
Authors:HUANG Xue -jun  HUANG Min  GONG Mei -en
Institution:The 2nd Affiliated Hospital of Guangzhou Medical College, Guangdong 510260, China
Abstract:Objective:To explore efficacy and side effects of venlafaxine in the treatment of depression.Methods:46 outpatients with a diagnosis of depression according to CCMD-3 were involved in this study for 8 weeks.Effects and side reactions were evaluated with HAMD,CGI-SI and TESS before and after the treatment.Results: Findings indicated that total efficacy of venlafaxine was91.6%.Conclusions: Venlafaxine is an effective and safe antidepressant.It is suggested that venlafaxine could be used as a first-line antidepressant in the treatment of depression.
Keywords:Venlafaxine  Depression  Treatment
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