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子宫内膜癌患者TSGF表达与细胞增殖的关系
引用本文:虞斌,许培箴,吴贤,王秋伟,周红,董一善.子宫内膜癌患者TSGF表达与细胞增殖的关系[J].中国妇幼保健,2007,22(8):1087-1088.
作者姓名:虞斌  许培箴  吴贤  王秋伟  周红  董一善
作者单位:江苏省常州市妇幼保健院,213003
基金项目:江苏省常州市科技局科研项目
摘    要:目的:探讨血清TSGF检测对子宫内膜癌的应用价值及其与细胞增殖的关系。方法:对30例子宫内膜癌患者术前外周血TSGF进行检测,同时对肿瘤组织DNA含量进行分析。结果:①子宫内膜癌患者血清TSGF含量及阳性率明显升高,敏感性为64.9%,特异性为62.5%,阳性预测值61.5%,阴性预测值65.8%,正确诊断率63.6%;②TSGF阳性者肿瘤细胞SPF明显升高,显著高于TSGF阴性者(P<0.05),PI指数略有上升,但无显著性差异(P>0.05),三者呈平行关系。结论:血清TSGF检测对子宫内膜癌具有一定的诊断价值,并与肿瘤细胞的增殖有关。

关 键 词:子宫内膜癌  TSGF  DNA  SPF  PI
文章编号:1001-4411(2007)08-1087-02
修稿时间:2005年12月5日

Examination of TSGF and its role in cell proliferation in carcinoma of endometrium
YU Bin,XU Pei-Zhen,WU Xian,et al..Examination of TSGF and its role in cell proliferation in carcinoma of endometrium[J].Maternal and Child Health Care of China,2007,22(8):1087-1088.
Authors:YU Bin  XU Pei-Zhen  WU Xian  
Institution:YU Bin,XU Pei-Zhen,WU Xian,et al.Maternity and Infant Health Hospital of Changzhou,Changzhou 213003,Jiangsu,China
Abstract:Objective:To estimate the clinical value of tumor specific growth factor(TSGF) in the diagnosis and monitoring of carcinoma of endometrium.Methods:The level of TSGF of the patients of carcinoma of endometrium and the content of DNA in tumor cell were detected.Results:① The level and the positive rate of TSGF for carcinoma of endometrium was significantly higher than that in other group(P<0.05).The sensitivity and specificity were 64.9% and 62.5%.②The SPF and PI raised in the patients whose TSGF were electropositive,higher than those of the women whose TSGF were negative.They were parallel.Conclusion:Serum TSGF level is helpful in diagnosis of carcinoma of endometrium,and related with the cell proliferation.
Keywords:TSGF  DNA  SPF  PI
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