A new furanoxanthone from the stem bark of Calophyllum inophyllum |
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Authors: | Ee Gwendoline Cheng Lian Mah Siau Hui Rahmani Mawardi Taufiq-Yap Yun Hin Teh Soek Sin Lim Yang Mooi |
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Affiliation: | Department of Chemistry, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia. gwen@science.upm.edu.my |
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Abstract: | The stem bark extracts of Calophyllum inophyllum furnished one new furanoxanthone, inophinnin (1), in addition to inophyllin A (2), macluraxanthone (3), pyranojacareubin (4), 4-hydroxyxanthone, friedelin, stigmasterol, and betulinic acid. The structures of these compounds were determined by spectroscopic analysis of 1D and 2D NMR spectral data ((1)H, (13)C, DEPT, COSY, HMQC, and HMBC) while EI-MS gave the molecular mass. The new xanthone, inophinnin (1), exhibited some anti-inflammatory activity in nitric oxide assay. |
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