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藏药云南兔耳草的化学成分研究(Ⅱ)
引用本文:杨丽娟,羊晓东,赵静峰,李良. 藏药云南兔耳草的化学成分研究(Ⅱ)[J]. 中药材, 2006, 29(2): 128-130
作者姓名:杨丽娟  羊晓东  赵静峰  李良
作者单位:1. 云南民族大学化学与生物技术学院,云南,昆明,650031
2. 云南大学药学院生物制药创新人才培养基地,云南,昆明,650091
基金项目:云南省教育厅资助项目;云南大学校科研和教改项目
摘    要:目的:提取、分离鉴定云南兔耳草的化学成分。方法:乙醇冷浸提取,氯仿、正丁醇依次萃取,硅胶柱层析分离纯化,通过理化常数和波谱分析鉴定化合物结构。结果:分离得到7个化合物,分别鉴定为artselaeroside A(1),3-羟基-5-甲氧基苯甲醇(3-hydroxy-5-m ethoxy-benzyl alcohol,2),对羟基苯乙醇(tyrosol,3),9′-顺-十八烯酸甘油酯(glycerin-9-′Z-octadecaenate,4),二十二酸甘油酯(glycerin-docosanate,5),二十四酸甘油酯(glycerin-tetracosanate,6),二十四烷酸(tetracosanoic ac id,7)。结论:以上化合物均为首次从该植物中分离得到。

关 键 词:云南兔耳草  玄参科  化学成分
文章编号:1001-4454(2006)02-0128-03
收稿时间:2005-09-26
修稿时间:2005-09-26

Studies on the Chemical Constituents of Lagotis yunnanensis (Ⅱ)
YANG Li-juan,YANG Xiao-dong,ZHAO Jing-feng,LI Liang. Studies on the Chemical Constituents of Lagotis yunnanensis (Ⅱ)[J]. Journal of Chinese medicinal materials, 2006, 29(2): 128-130
Authors:YANG Li-juan  YANG Xiao-dong  ZHAO Jing-feng  LI Liang
Affiliation:1. School of Chemistry afld Bio-Science, Yunnan Nationalities Universily, Knnming 650031 ,China; 2. School of Pharmacy, Center for Advanced Studies of Medicinal and Organic ChemistIT, Yunnan University, Kunming 650091 ,China
Abstract:OBJECTIVE: To study the chemical constituents of Lagotis yunnanensis W. W. Smith. METHODS: Compounds were isolated from the ethanolic extract of the title herb by silica gel column chromatography, and their structures were identified by physical and chemical evidences and spectral methods. RESULTS: Seven compounds were isolated and identified as artselaeroside A (1),3-hydroxy-5-methoxy-benzyl alcohol (2), tyrosol (3), glycerin-9'-Z-octadecaenate (4), glycerin-docosanate (5), glycerin-tetracosanate (6), tetracosanoic acid (7), respectively. CONCLUSION: All the compounds were isolated from this plant for the first time.
Keywords:Lagotis yunnanensis W.W.Smith  Scrophulariaceae  Chemical constituents
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