宫腔镜术中右美托咪定复合异丙酚的麻醉效果

目的 探讨分析宫腔镜手术中联合应用右美托咪定对患者生命体征、不良反应及异丙酚用量的影响.方法 选取于2014年8月至2016年7月来南海区妇幼保健院就诊的行宫腔镜手术的患者100例,根据随机数字法将所有患者分为观察组和对照组,每组各50例.观察组患者麻醉使用右美托咪定、舒芬太尼和异丙酚,对照组患者麻醉使用等量生理盐水、舒芬太尼和异丙酚.记录两组患者的心率、平均动脉压、异丙酚的用量、不良反应.结果 观察组和对照组患者麻醉前心率和平均动脉压比较,差异无统计学意义(P＞0.05).麻醉后及扩宫时观察组患者的心率、平均动脉压明显低于对照组,差异有统计学意义(心率:t值分别为-2.942、-8.474,均P＜0.01;平均动脉压:t值分别为-6.128、-7.889,均P＜0.01).对照组患者术中异丙酚用量为(168.97±39.21) mg,观察组患者畀丙酚用量为(144.23 ±25.17)mg,比较差异有统计学意义(t=3.755,P＜0.001).对照组患者的扩宫体动和呼吸抑制发生率明显高于观察组患者(x2值分别为28.571、4 762,均P＜0.05).两组患者低血压和心动过缓发生率比较,差异无统计学意义(x2值分别为1.000、2 554,均P＞0.05).结论 宫腔镜手术中联合使用右美托咪定能稳定患者的生命体征,减少术中异丙酚的用量和不良反应,麻醉效果良好.

Anesthetic effect of dexmedetomidine combined with propofol in hysteroscopic surgery

Objective To discuss the influence of combined use of dexmedetomidine on vital signs,adverse reactions and propofol dosage in hysteroscopic surgery.Methods Totally 100 patients accepting hysteroscopic surgery in Nanhai District Maternity and Children's Hospital of Foshan during August 2014 to July 2016 were selected.All patients were divided into observation group and control group according to random number method with 50 cases in each group.In the observation group,patients were anesthetized with dexmedetomidine,sufentanil and propofol,while in the control group,patients was anesthetized with an equal volume of saline,sufentanil and propofol.The heart rate,mean arterial pressure,propofol dosage,and adverse effects were recorded in two groups.Results There was no significant difference in heart rate and mean arterial pressure between two groups before anesthesia (P ＞ 0.05).The heart rate and mean arterial pressure of the observation group were significantly lower than those of the control group after anesthesia and cervical enlarged.The differences were statistically significant (heart rate:t value was-2.942 and-8.474,respectively,both P ＜0.01;mean arterial pressure:t value was-6.128 and-7.889,respectively,both P ＜ 0.01).In the control group,the propofol dosage was 168.97 ± 39.21mg,while in the observation group was 144.23 ±25.17mg.The difference was statistically significant (t =3.755,P ＜0.001).The incidence of body moving stimulated by cervix dilated and respiratory depression in the control group was significantly higher than that in tbe observation group (x2 value was 28.571 and 4.762,respectively,both P ＜0.05).There was no significant difference in the incidence of hypotension and bradycardia between two groups (x2 value was 1.000 and 2.554,respectively,both P ＞ 0.05).Conclusion Dexmedetomidine combined with propofol in hysteroscopic surgery can stabilize patient's vital signs,reduce the dosage of propofol and adverse reactions during surgery and obtain good anesthesia effect.