免疫治疗调节变应性鼻炎外周血调节性T细胞表达

变应性鼻炎是机体接触变应原后主要由免疫球蛋白IgE介导的鼻黏膜变态反应性炎症，大量实验研究表明变应性鼻炎是由于Thl/Th2失衡引起的。近年来研究表明Thl7与调节性T细胞在变应性鼻炎的免疫反应的发生和发展中有着重要的作用。调节性T细胞功能降低时Th2反应占优势。研究还表明变应性鼻炎患者的外周血中调节性T细胞的表达是降低的，且在进行免疫治疗后，其外周血的CD4+CD25+调节性T细胞细胞表达较之前增多。

Immunotherapy to adjust allergic rhinitis research progress of peripheral blood Treg expression

Allergic rhinitis is the body after exposure to allergens is mainly composed of immunoglobulin IgE mediated the nasal mucosa of allergic inflammation,a large number of studies have shown that AR is caused due to Thl/Th2 imbalance.Allergic rhinitis is the body after exposure to allergens is mainly composed of immunoglobulin IgE mediated the nasal mucosa of allergic inflammation,a large number of studies have shown that AR is caused due to Thl/Th2 imbalance.Reduce the Th2 reaction dominant Treg function.Studies have also shown that the peripheral blood of patients with AR Treg expression is reduced,and after immune therapy,the peripheral blood CD4+CD25+Treg cells express more earlier.