| 耳蜗血管纹缘细胞三磷酸腺苷释放机制 |
| |
| 引用本文： | 刘斌,谢仁炜,刘君.耳蜗血管纹缘细胞三磷酸腺苷释放机制[J].国际耳鼻咽喉头颈外科杂志,2017,41(3):125. |
| |
| 作者姓名： | 刘斌 谢仁炜 刘君 |
| |
| 作者单位： | 1. 200127,上海交通大学医学院附属仁济医院耳鼻咽喉科;2. 200431,上海市宝山区仁和医院医务部 |
| |
| 基金项目： | 国家自然科学基金资助项目(81600797)National Natural Science Foundation of China |
| |
| 摘 要： | 三磷酸腺苷（adenosine triphosphate，ATP）被认为是耳蜗中一种重要的信号分子，可以作为共同递质和（或）神经调节物质发挥耳蜗的各种生理功能。目前已证实新生大鼠耳蜗血管纹缘细胞内的ATP囊泡为溶酶体，可以释放ATP。然而，缘细胞释放ATP的机制还未完全阐明，本文结合国内外文献就耳蜗缘细胞中ATP释放机制的研究现状做一综述。
|
| 关 键 词： | 三磷酸腺苷 耳蜗 溶酶体 缘细胞 |
Current research status on the mechanism of ATP release from marginal cells of cochlear atria vasculararis |
| |
| Liu Bin,Xie Renwei,Liu Jun.Current research status on the mechanism of ATP release from marginal cells of cochlear atria vasculararis[J].International Journal of Otolaryngology-Head and Neck Surgery,2017,41(3):125. |
| |
| Authors: | Liu Bin Xie Renwei Liu Jun |
| |
| Abstract: | Adenosine triphosphate (ATP),an important extracellular nucleotide in the cochlear,has been shown to affect several kinds of physical functions of cochlea,where ATP acts as a co-transmitter and/or neuromodulator.It is confirmed that ATP-containing vesicles in stria vascular marginal cell cytoplasm in neonatal rat cochlea are lysosomes,which release ATP.However,the mechanism for ATP release remains unclear.Based on the literatures at home and abroad,the current research status of ATP release mechanism in the cochlear marginal cells is reviewed. |
| |
| Keywords: | adenosine triphosphate Cochlea Lysosome marginal cell |
| 本文献已被 万方数据 等数据库收录！ |
| 点击此处可从《国际耳鼻咽喉头颈外科杂志》浏览原始摘要信息 |
| 点击此处可从《国际耳鼻咽喉头颈外科杂志》下载免费的PDF全文 |
