单纯性肥胖儿童脂肪肝相关危险因素分析

目的 探讨导致单纯性肥胖儿童出现脂肪肝的相关危险因素,为单纯性肥胖儿童脂肪肝的预防及治疗提供一定的指导.方法 选择2011年7月至2012年11月在西安交通大学第二附属医院小儿内分泌专科门诊确诊的121例单纯性肥胖儿童为研究对象.将121例单纯性肥胖儿童根据腹部B超影像学检查结果分为脂肪肝组和非脂肪肝组,测量所有儿童的身高、体重,计算体质量指数(BMI)值;空腹8～ 12小时后,行肝脏B超检查.对所有肥胖儿童进行问卷调查,调查内容包括基本情况登记、儿童的一般情况、家庭情况、体格检查4部分.结果 脂肪肝总检出率为53.72％,其中男性患儿脂肪肝检出率(60.23％)显著高于女性患儿(36.36％),差异有统计学意义(t=5.497,P＜0.05).脂肪肝组患儿进食快餐频率以及吃零食、饮料频率高于非脂肪肝组患儿,经比较差异具有统计学意义(x2值分别为3.54、4.61,均P＜0.05).两组患儿的父母饮食习惯以及家族中糖尿病、高血压、高血脂、冠心病的发病率比较,差异均无统计学意义(均P＞ 0.05).结论 肥胖儿童脂肪肝的检出率较高,超过半数以上的肥胖儿童为脂肪肝患者,儿童个人的饮食习惯在脂肪肝的发生中起到重要作用,应引起重视.

Analysis of risk factors of fatty liver in simple obese children

Objective To explore the risk factors of fatty liver in children with simple obesity and to provide some guidance for the prevention and treatment of fatty liver in simple obese children.Methods A total of 121 simple obese children were enrolled in this study from July 2011 to November 2012 in the Second Affiliated Hospital of Xi'an Jiaotong University.They were divided into fatty liver group and non-fatty liver group according to abdominal B uhrasonography.The height,weight and body mass index (BMI) of all children were measured.Fasting 8 to 12 hours liver B ultrasound examination was performed.A questionnaire survey was conducted among all the cases.The survey included basic information registration,general situation of children,family situation and physical examination.Results The total detection rate of fatty liver was 53.72％.The detection rate of fatty liver in male children (60.23％) was significantly higher than that in female children (36.36％),and the difference was statistically significant (t =5.497,P ＜ 0.05).The frequency of eating fast food and eating snacks in children with fatty liver was higher than those in non-fatty liver group,and the difference was statistically significant (x2 value was 3.54 and 4.61,respectively,both P ＜ 0.05).There was no significant difference in parental dietary,incidence of diabetes mellitus,hypertension,hyperlipidemia and coronary heart disease in family between two groups (all P ＞ 0.05).Conclusion The detection rate of fatty liver in obese children is high.More than half of obese children are patients with fatty liver.Children's eating habits play an important role in the development of fatty liver,so it should attract attention.