| 变应原特异性免疫治疗在儿童变应性疾病中的应用 |
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| 引用本文： | 张文馨.变应原特异性免疫治疗在儿童变应性疾病中的应用[J].国际儿科学杂志,2017,44(2). |
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| 作者姓名： | 张文馨 |
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| 作者单位： | 210008,南京医科大学附属南京儿童医院 |
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| 摘 要： | 变应原特异性免疫治疗是一种应用于IgE介导的变应性疾病的脱敏疗法,其主要和药物治疗联合使用,治疗过敏原无法避免的变应性哮喘、变应性鼻炎及特发性皮炎患者,也是可能改变变应性疾病自然病程的治疗方法.但是免疫治疗在儿童过敏性疾病中的应用尚存在争议,研究较少.现就变应原特异性免疫治疗的作用机制及其在儿童变应性疾病中的临床疗效和安全性进行综述.
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| 关 键 词： | 变应原特异性免疫治疗 儿童 机制 临床疗效 安全性 |
Application of allergen specific immunotherapy in children with allergic diseases |
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| Zhang Wenxin.Application of allergen specific immunotherapy in children with allergic diseases[J].International Journal of Pediatrics,2017,44(2). |
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| Authors: | Zhang Wenxin |
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| Abstract: | Allergen specific immunotherapy(AIT) is a desensitization treatment for IgE-mediated allergic diseases.Combined with pharmacological therapy,AIT is used to treat allergic asthma,allergic rhinitis and atopic dermatitis caused by allergens that cannot be avoided.AIT is the only treatment modality that can alter the natural course of allergic disease.However,because of the lack of studies,there still exists controversy about the application of immunotherapy in children with allergic diseases.The mechanism ofAIT,its clinical efficacy and safety in children with allergic diseases are reviewed. |
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| Keywords: | Allergen specific immunotherapy Children Mechanism Clinical efficacy Safety |
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