In Vitro Effects of Pentifin on Some Neurotransmitter Systems in the Brain |
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| Authors: | E. N. Gorbatova S. G. Dagaev V. B. Dolgo-Saburov F. S. Dukhovich |
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| Affiliation: | (1) State Institute of Organic Chemistry and Technology, Moscow;(2) Institute of Toxicology, Russian Ministry of Health, St. Petersburg |
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| Abstract: | Pentifin and dopamine D1 receptor antagonist SCH-23390 possess similar pharmacological properties. In the present work we studied in vitro effects of Pentifin on dopamine receptors. Experiments on rat ductus deferents showed that Pentifin acts as a weak ligand of dopamine receptors. Our results indicate that the antihaloperidol effect of Pentifin is not related to the blockade of dopamine receptors. |
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| Keywords: | dopamine receptors acetylcholine receptors epinephrine receptors |
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