Cellular FLICE-like inhibitory protein (c-FLIP): a novel target for Taxol-induced apoptosis |
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| Authors: | Day Travis W Najafi Farhad Wu Ching-Huang Safa Ahmad R |
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| Affiliation: | Department of Pharmacology and Toxicology, Indiana University Cancer Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA. |
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| Abstract: | |
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| Keywords: | MT, microtubule MAPK, smitogen-activated protein kinases PTK, protein tyrosine kinases TNF-α, tumor necrosis factor-α TNFR1, tumor necrosis factor-α receptor 1 TRAIL, tumor necrosis factor-related apoptosis-inducing ligand AIF, apoptosis-inducing factor IAP, an inhibitor of apoptosis protein Apaf1, apoptotic proteinase activating factor-1 PKC, protein kinase C PARP, poly(ADP-ribose) polymerase DFF45, DNA fragmentation factor-45 ROS, reactive oxygen species c-FLIP, cellular FLICE-like inhibitory protein PTP, permeability transition pore PI, propidium iodide |
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