Validation of the EORTC QLQ-C30 and EORTC QLQ-H&N35 in patients with laryngeal cancer after surgery |
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| Authors: | Singer Susanne Wollbrück Dorit Wulke Cornelia Dietz Andreas Klemm Eckart Oeken Jens Meister Eberhard F Gudziol Hilmar Bindewald Julian Schwarz Reinhold |
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| Institution: | Department of Social Medicine, University of Leipzig, Leipzig, Germany. susanne.singer@medizin.uni-leipzig.de |
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| Abstract: | Background. The aim of this study was to test the validity of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire, Core Module (QLQ‐C30) and Head and Neck Module (QLQ‐H&N35) for patients who have undergone surgery due to laryngeal cancer. Methods. A total of 323 patients from 6 different centers in Germany who had been operated on completed the QLQ‐C30 and the QLQ‐H&N35 in addition to being surveyed in a personal interview. Results. Multitrait scaling analysis confirmed the proposed scale structure of both questionnaires. Cronbach's alpha of the QLQ‐C30 scales ranged from 0.64 (Cognitive Functioning) to 0.94 (Global Health Status); the alpha of the QLQ‐H&N35 ranged from 0.55 (Speech) to 0.90 (Sexuality). Known‐groups comparisons showed multiple differences in sociodemographic and clinical variables. Conclusion. It can be concluded that the QLQ‐H&N35, in conjunction with the QLQ‐C30, is a reliable instrument that is able to differentiate between diverse groups of patients with laryngeal cancer after surgery. © 2008 Wiley Periodicals, Inc. Head Neck, 2009 |
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| Keywords: | validation health‐related quality of life laryngeal cancer EORTC QLQ‐H&N35 EORTC QLQ‐C30 |
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