虫草菌丝对酒精性脂肪肝大鼠治疗效果的研究

目的探讨虫草菌丝对酒精性脂肪肝大鼠模型的治疗效果。方法将40只SD大鼠随机分成4组:正常对照组、模型组、饮食治疗组和虫草菌丝治疗组。实验末处死所有大鼠,检测血清天门冬氨酸氨基转移酶(AST)、丙氨酸氨基转移酶(ALT)、总胆固醇(TC)、三酰甘油(TG)。同时行肝脏病理组织学检查。结果虫草菌丝治疗组大鼠血清AST、ALT、TC、TG明显低于模型组。虫草菌丝组大鼠肝细胞脂肪变及炎症明显改善。结论虫草菌丝对酒精性脂肪肝有治疗作用。

To Explore the Effect of Cordyceps Sinesis on Alcoholic Fatty Liver in Rats

Objective To explore the effect of cordyceps sinesis( CS) on alcoholic fatty liver (AFL) in rats. Methods 40 SD rats were divided randomly into four groups: Normal control group; model group; dietary control group; CS group. By the end of the experiment, all rats were sacrificed. Level of aspartate aminotransferase (AST), alanine aminotransferase (ALT), total cholesterol (TC) and triglyeride (TG) in serum were measured. Liver sample were analyzed for histopathology with microscope. Results Contrast with model group, the level of AST, ALT, in serum decreased in CS group markedly(P<0.01). In CS group, the steatosis state and inflammation of level were improved. Conclusion Cordyceps sinesis have therapeutic effects on alcoholic fatty liver .