| 反相高效液相色谱法测定胃炎片中原儿茶醛的含量 |
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| 引用本文： | 王海龙,王宝全,赵庆华.反相高效液相色谱法测定胃炎片中原儿茶醛的含量[J].实用医药杂志(山东),2007,24(5):574-575. |
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| 作者姓名： | 王海龙 王宝全 赵庆华 |
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| 作者单位： | 济南军区联勤部药品仪器检验所,山东济南250022 |
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| 摘 要： | 目的建立胃炎片中原儿茶醛的含量测定方法。方法采用反相高效液相色谱法测定胃炎片中原儿茶醛的含量。采用日本Sil C18色谱柱,以甲醇-1%醋酸水溶液(13∶87)为流动相,流速为1ml/min,检测波长280nm。结果原儿茶醛在0．0762～0．4572μg线性关系良好,r=0．9999,平均回收率为101．1%, RSD=0．70%。结论该方法简便、灵敏、准确,可作为胃炎片的质量控制方法。
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| 关 键 词： | 高效液相色谱 胃炎片 原儿茶醛 |
| 收稿时间： | 2006-12-08 |
| 修稿时间： | 2006年12月8日 |
Determination of protocatechuic aldehyde in Weiyan tablets by RP-HPLC |
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| WANG Hai-long,WANG Bao-quan,ZHAO Qing-hua.Determination of protocatechuic aldehyde in Weiyan tablets by RP-HPLC[J].Practical Journal of Medicine & Pharmacy,2007,24(5):574-575. |
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| Authors: | WANG Hai-long WANG Bao-quan ZHAO Qing-hua |
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| Abstract: | Objective To establish a method for the determination of protocatechuic aldehyde in Weiyan tablets.Methods RP-HPLC method was developed for the determination of protocatechuic aldehyde in Weiyan tablets on Japanese Sil C18 column,with methanol-1% acetic acid(13:87)as a mobile phase(1mL/min)and detection wavelength at 280nm.Results The linear range of protocatechuic aldehyde was 0.0762-0.45721μg and the correlation coefficient was 0.9999.The average recovery rate was 101.1%,RSD was 0.70%(n=6).Conclusion The method is convenient and accurate,and can be used control the tablets quality. |
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| Keywords: | HPLC Weiyan tablets Protoeatechuic aldehyde |
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