葛根素注射液治疗椎-基底动脉供血不足42例疗效观察

目的观察葛根素注射液在治疗椎-基底动脉供血不足(VBI)的临床效果。方法84例椎-基底动脉供血不足患者随机分成2组,治疗组42例给予葛根素注射液0.4 g+生理盐水250 ml,静脉点滴,每日1次,2周为1疗程。对照组42例给予丹参注射液30 ml+生理盐水250 ml,静脉点滴,每日1次,2周为1疗程。两组于治疗前后作血液流变学测定。结果治疗组总有效率明显高于对照组(P<0.05)。两组治疗前各指标比较无显著差异(P>0.05),对照组各指标治疗后与治疗前比较无显著差异(P>0.05),治疗组治疗后各指标与治疗前比较均有显著差异(P<0.01),两组治疗后各指标比较均有显著差异(P<0.05)。结论葛根素治疗椎-基底动脉供血不足疗效确切,且能改善患者血流动力学。

Effect of kakkonein injection in treatment of 42 cases of vertebrobasilar ischemia

Objective To observe clinical effectiveness of kakkonein injection in treatment of vertebrobasilar ischemia(VBI).Methods Eighty-four VBI patients were randomly divided into two groups: treatment group(n=42) were intravenously performed with 0.4g Kakkonein plus 250 ml normal sodium once daily for 2 weeks,30 ml Danshen parenteral solution plus 250ml normal sodium were intravenously performed once daily for 2 weeks in control group.Hemorrheology were determined pre-and post-treatment in two groups.Results Total effective rate in treatment group(92.86%)was obviously higher than that in control group(78.57%)(P<0.05).Every indexes were no significant difference in two groups before treatment(P>0.05),it were no significant difference of every indexes in control group pre-and post-treatment(P>0.05),indexes in treatment group was significant difference before treatment compared post-treatment(P<0.01),and there was significant difference of indexes in two groups post-treatmentt(P<0.05).Conclusion It is certain curative effects of kakkonein in treatment of VBI,which can improve hemodynamics.