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黄芪桂枝五物汤加味治疗类风湿关节炎临床研究
引用本文:韩旭. 黄芪桂枝五物汤加味治疗类风湿关节炎临床研究[J]. 河南中医, 2021, 41(1): 49-52
作者姓名:韩旭
作者单位:安阳市第二人民医院,河南安阳455000
基金项目:河南省科学研究与专项课题项目(2017ZY2057)。
摘    要:目的:观察黄芪桂枝五物汤加味治疗类风湿关节炎的临床疗效及其对患者血沉(erythrocyte sedimentation rate,ESR)和C反应蛋白(C reactive protein,CRP)水平的影响.方法:将76例类风湿关节炎患者按照随机数字表法分为对照组和治疗组,每组各38例.对照组应用氟米特片、甲氨蝶呤...

关 键 词:类风湿关节炎  黄芪桂枝五物汤加味  《金匮要略》  张仲景

Clinical Study of Flavored Astragalus and Cinnamon Twig Five Substances Decoction in the Treatment of Rheumatoid Arthritis
HAN Xu. Clinical Study of Flavored Astragalus and Cinnamon Twig Five Substances Decoction in the Treatment of Rheumatoid Arthritis[J]. Henan Traditional Chinese Medicine, 2021, 41(1): 49-52
Authors:HAN Xu
Affiliation:(The Second People's Hospital of Anyang,Anyang,Henan,China,455000)
Abstract:Objective:To observe the clinical curative effect of Flavored Astragalus and Cinnamon Twig Five Substances Decoction on rheumatoid arthritis(RA)and its influence on ESR and CRP of the patients.Methods:A total of 76 patients with RA were randomly divided into the control group and the treatment group,with 38 cases in each group.The control group was treated with routine Western medicine such as flunomide tablets and methotrexate,while the treatment group was treated with Flavored Astragalus and Cinnamon Twig Five Substances Decoction on the basis of the control group.The levels of erythrocyte sedimentation rate(ESR)and C reactive protein(CRP)of the two groups were detected before and after the treatment.The clinical efficacy,disease progression and clinical symptom score change of the two groups were compared.Results:The levels of CRP and ESR in the two groups after the treatment were lower than those of the same group before the treatment,and the above indexes in the treatment group were lower than those in the control group after treatment,and all the differences were statistically significant(P<0.05).The effective rate of the control group was 81.6%,and that of the treatment group was 92.1%.The difference was statistically significant(P<0.05).The number of patients in remission stage and mild active stage after the treatment in the two groups was more than that before the treatment in the same group,and the number of cases in remission stage in the treatment group was more than that in the control group,the difference was statistically significant(P<0.05).The scores of joint pain,morning stiffness,tenderness,swelling and dysfunction in the treatment group were lower than those in the control group,and all the differences were statistically significant(P<0.05).Conclusion:In terms of RA,Flavored Astragalus and Cinnamon Twig Five Substances Decoction can improve the clinical symptoms and CRP,ESR levels,and slow down the disease progression.
Keywords:rheumatoid arthritis(RA)  Flavored Astragalus and Cinnamon Twig Five Substances Decoction  Synopsis of the Golden Chamber  Zhang Zhong-jing
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