原发性大肠恶性淋巴瘤临床、内镜与病理特点

目的 搪塞原发性大肠恶性淋巴瘤（ＰＣＭＬ）的临床表现、内镜和病理特点。方法 采用血常规及血型检测,Ｘ线检查、内镜检查,最终均得到手术和病理证实。结果 ２４例ＰＣＭＬ中临床表现以腹痛、体重下降、发热、腹块、便血和大便习惯改变为主。病变位迂回在盲部９例（３７．５％）,直肠１例（４．２％）。内镜下表现为隆起９／１６例（５６．２％）、浸润型４／１６型（２５．０％）,溃疡型３／１６例（１８．８％）,与术后分

Primary colorectal malignant lymphoma : a report on clinical , endoscopic and pathologic features

Objective The clinical manifestations , endoscopic and pathologic characteristics of primary colorectal malignant lymphoma ( PCML ) were discussed . Methods 24 patients with PCML received assays of blood for routine and typing , roentgenography ,endoscopy and final confirmation by surgery and pathology . Results The clinical presentations included abdominal pain ( n=22, 91.6%) , loss of weight ( n=20, 80.3%) ,fever (n=17,70.8%) abdominal mass(n=16,66.7%),blood in stools ( n=14, 80.3%), and change in bowel movements ( n=14, 58.4%) . Not a few tumors located at ileocecal region ( n=9, 37.1%) , only one lymphoma situated at rectum ( 4.2%) . Of the 16 cases examined by endoscopy , the scopic typing as protruding , infiltrative and ulcerative lesions accounted for 56.2%( n=9) , 25.0%( n=4 ) and 18.8%( n=3 ) respectively. 81.3 percent of the typing being in line with postoperative naked eye classification . But the coincidence rate of endoscopic biopsy with pathology of resected specimen reduced to 62.5 percent . The tumor might originate from the following organisms : B cell ( n=18 , 75.0%) , T cell ( n=5 , 20.8%) and histocyte ( n=1, 4.2%) , capable of being classified into centrocytic malignant lymphoma ( n=9, 37.5%) , small cell malignant lymphoma ( n=5, 20.8%) , T cell malignant lymphoma ( n=5, 20.8%) , centroblastic centrocytic malignant lymphoma ( n=1, 4.2%) and histiocytic malignant lymphoma ( n=1, 4.2%) .Conclusion Abdominal pain and mass, loss of weight , fever , bloody stools and change of bowel habit constituted the clinical aspects of PCML , which affecting frequently the distal ileum and cecum as protruding growth with centrocytes and T cells as well . Its pathogenesis may be attributed to heredity