不明原因发热患者122例临床诊断及病因分析

目的探讨不明原因发热（FUO）的病因。方法回顾性分析122例FUO患者的病因。结果122例FUO患者明确诊断者有106例，确诊率86．9％。其中感染性疾病61例（包括细菌感染42例，病毒感染14例，真菌感染3例，其他2例），非感染性疾病45例（包括血管结缔组织病18例，肿瘤性疾病22例，其他疾病5例）。最后仍有16例患者诊断不明。结论感染性疾病仍是FUO的主要病因，结核病、结缔组织病和肿瘤性疾病在本组FUO病因中也占重要地位，大多数FUO经仔细的临床检查可以得到确诊。

Analysis of Diagnostic and Etiological Factors in Patients with Fever of Unknown Origin

Objective To investigate the diagnostic and etiological factors in patients with fever of unknown origin（FUO）. Methods The clinical data of 122 patients with FUO, who were treated in hospital since March 2005 to May 2007, were retrospectively analyzed. Results Among the 122 patients, 106 patients were definitely diagnosed（ 86.9% ）. Among the 106 definite diagnosis patients,61 cases were infectious disease（42 cases were bacterial infectionl4 cases were virus infection,3 cases were fungus infection and 2 case belonged to other disease） ,45 cases were non-infections disease（ 18 cases were connective tissue disease,22 cases were malignant tumor and 5 cases belonged to other diseases）. 16 cases remained origin unknown until they were discharged from hospital. Conclusion Infection is the main cause of FUO ; the incidence of tuberculosis was the highest among the various infectious diseases as the cause of FUO; patients with extrapulmonary tuberculosis presented more frequently with FUO than those with intra pulmonary tuberculosis. CVD and malignancy were also major causes of FUO, and the incidence of malignancy increased with the lapse of time.