| 凤尾蕨属6种植物不同部位体外抗肿瘤作用研究 |
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| 引用本文： | 龚先玲,苟占平,梁念慈,刘义,李立.凤尾蕨属6种植物不同部位体外抗肿瘤作用研究[J].辽宁中医药大学学报,2011(1):67-70. |
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| 作者姓名： | 龚先玲 苟占平 梁念慈 刘义 李立 |
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| 作者单位： | 广东医学院天然药物研究与开发重点实验室;广东医学院药学院; |
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| 基金项目： | 广东省自然科学基金项目(8152402301000019); 广东省科技计划项目(2009B030801336); 东莞市高等院校科研机构科技计划项目(2008108101050) |
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| 摘 要： | 目的:对凤尾蕨属6种药用植物不同部位抗肿瘤作用进行筛选。方法:以人鼻咽癌细胞CNE-2Z为筛选模型,采用MTT法对凤尾蕨属6种药用植物不同溶剂萃取部位进行体外抗肿瘤活性测试。结果:半边旗的乙酸乙酯萃取物、正丁醇萃取物,刺齿半边旗的石油醚萃取物、乙酸乙酯萃取物、正丁醇萃取物,剑叶凤尾蕨的乙酸乙酯萃取物,线羽凤尾蕨的正丁醇萃取物对人鼻咽癌细胞CNE-2Z增殖有明显的抑制作用。结论:上述凤尾蕨属4种药用植物的萃取物具有较好的体外抗肿瘤活性,是其抗肿瘤作用的有效部位。
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| 关 键 词： | 凤尾蕨属 体外抗肿瘤作用 有效部位 |
Screening of Antitumor Activityfrom Six Species of Pteris |
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| GONG Xian-ling,GOU Zhan-ping,LIANG Nian-ci,LIU Yi,LI Li.Screening of Antitumor Activityfrom Six Species of Pteris[J].Journal of Liaoning University of Traditional Chinese Medicine,2011(1):67-70. |
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| Authors: | GONG Xian-ling GOU Zhan-ping LIANG Nian-ci LIU Yi LI Li |
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| Institution: | GONG Xian-ling1,GOU Zhan-ping1,2,LIANG Nian-ci1,LIU Yi1,LI Li1(1.Guangdong Key Laboratory for Research and Development of Natural Drugs,Guangdong Medical College,Zhanjiang 524023,Guangdong,China,2.Pharmacology College of Guangdong Medical College,Dongguan 523808,China) |
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| Abstract: | Objective:To screen the active fraction with anticancer effect from six species of Pteris.Methods:The samples were prepared by solvent extraction.The six plants were extracted respectively with ethanol at first,and then every ethanolic extract was separated with petroleum ether,ethyl acetate,n-Butyl alcohol in turn to get three fractions.The antitumor activities of 18 kinds of extract in vitro were determined by MTT assay.Results:Ethyl acetate and n-BuOH extract of Pteris semipinnta L.,petroleum ether,Ethyl... |
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| Keywords: | Pteris antitumor effect active fraction |
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