Improved accuracy in estimation of left ventricular function parameters from QGS software with Tc-99m tetrofosmin gated-SPECT: a multivariate analysis |
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Authors: | Atsutaka Okizaki Noriyuki Shuke Junichi Sato Yukio Ishikawa Wakako Yamamoto Kenjiro Kikuchi Tamio Aburano |
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Institution: | (1) Department of Radiology, Asahikawa Medical College, 2-1-1-1 Midorigaokahigashi, 078-8510 Asahikawa, Japan;(2) First Department of Internal Medicine, Asahikawa Medical College, 2-1-1-1 Midorigaokahigashi, 078-8510 Asahikawa, Japan |
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Abstract: | The purpose of this study was to verify whether the accuracy of left ventricular parameters related to left ventricular function
from gated-SPECT improved or not, using multivariate analysis.Methods: Ninety-six patients with cardiovascular diseases were studied. Gated-SPECT with the QGS software and left ventriculography
(LVG) were performed to obtain left ventricular ejection fraction (LVEF), end-diastolic volume (EDV) and end-systolic volume
(ESV). Then, multivariate analyses were performed to determine empirical formulas for predicting these parameters. The calculated
values of left ventricular parameters were compared with those obtained directly from the QGS software and LVG.Results: Multivariate analyses were able to improve accuracy in estimation of LVEF, EDV and ESV. Statistically significant improvement
was seen in LVEF (from r=0.6965 to r=0.8093, p<0.05). Although not statistically significant, improvements in correlation
coefficients were seen in EDV (from r=0.7199 to r=0.7595, p=0.2750) and ESV (from r=0.5694 to r=0.5871, p=0.4281).Conclusion: The empirical equations with multivariate analysis improved the accuracy in estimating LVEF from gated-SPECT with the QGS
software. |
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Keywords: | QGS Tc-99m tetrofosmin multivariate analysis ejection fraction |
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