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HDL抗动脉粥样硬化的多功能性以及氧化修饰对其功能的影响
引用本文:张春妮,陈大宁,庄一义. HDL抗动脉粥样硬化的多功能性以及氧化修饰对其功能的影响[J]. 医学研究生学报, 2001, 14(Z1): 56-59
作者姓名:张春妮  陈大宁  庄一义
作者单位:南京军区南京总医院解放军医学检验中心,江苏南京,210002
摘    要:高密度脂蛋白(HDL)作为体内抗动脉硬化脂蛋白,不仅参与胆固醇逆向转运,尚具有其他多种抗动脉硬化功能。氧化修饰则从各个方面削弱高密度脂蛋白的抗动脉硬化效应。本文介绍高密度脂蛋白抗动脉硬化的多功能性以及氧化修饰对其功能的影响。

关 键 词:高密度脂蛋白  载脂蛋白AⅠ  氧化修饰;动脉粥样硬化
文章编号:1008-8199(2001)增刊-0056-04
修稿时间:2000-12-19

Multi-functional aspects of high density lipoprotein as an anti-atherogenic lipoprotein and the effect of oxidative modification on its function
ZHANG Chun-ni,CHEN Da-ning,ZHUANG Yi-yi. Multi-functional aspects of high density lipoprotein as an anti-atherogenic lipoprotein and the effect of oxidative modification on its function[J]. Bulletin of Medical Postgraduate, 2001, 14(Z1): 56-59
Authors:ZHANG Chun-ni  CHEN Da-ning  ZHUANG Yi-yi
Abstract:As an anti atherogenic lipoprotein in vivo , high density lipoprotein(HDL) mainly involves in cholesterol reverse transportation, recent studies have also revealed other aspects of HDL which might be linked to its anti atherogenic capacity. Whereas the oxidative modification of HDL may impair its anti atherogenic function. This paper was conducted to introduce the multi functional aspects of high density lipoprotein as an anti atherogenic lipoprotein and the effect of oxidative modification on its function.
Keywords:High density lipoprotein  Apolipoprotein  Oxidative modification  Atherosclerosis
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